Software Engineer - Core Infrastructure

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📍 San Mateo, CAFullTime

About this role

Genesis Therapeutics is building a world-class computational team to solve problems in drug discovery through machine learning, biophysical simulation, and computational chemistry. We are looking for an Infrastructure Engineer that is excited to help develop new medicines and play a critical role in building out our AI platform.

You Will

  • Work on our infrastructure team to maintain and grow our multi-cloud compute infrastructure that supports our ML model training, computational chemistry research, and ongoing drug discovery efforts

  • Build out our configuration and procedures for monitoring, resource allocation, and deployment automation, as we continue to grow our autoscaling compute clusters to handle larger workloads

  • Work on orchestration scheduling framework to increase our execution throughput, reliability, and compute utilization across heterogeneous pipelines

You Are

  • 5+ years of experience building and maintaining cloud infrastructure at scale, e.g. within AWS or GCP

  • Proficient with Python, Bash, Terraform, Ray and Kubernetes

  • Ideally, experience building and maintaining compute clusters running distributed ML training jobs with 1,000+ GPUs

  • Nice to have: hands-on experience with physical hardware + datacenter management

What We Offer

  • The opportunity to work on high impact infrastructure that is used to accelerate the discovery of new medicines

  • A world-class, tight-knit team of good-hearted people across software, machine learning, computational chemistry, medicinal chemistry, and biology

  • Competitive salary and equity. Medical, dental, and vision insurance, and a 401(k) program

About Genesis Molecular AI

Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company’s generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets.

Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.

Frequently Asked Questions

Is the salary disclosed for the Software Engineer - Core Infrastructure position at genesis-molecular-ai?
The salary for this Software Engineer - Core Infrastructure role at genesis-molecular-ai is not publicly listed. Click "Apply Now" to learn more about the compensation package on their official careers page.
Where is the Software Engineer - Core Infrastructure position at genesis-molecular-ai located?
This Software Engineer - Core Infrastructure role at genesis-molecular-ai is based in San Mateo, CA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Is the Software Engineer - Core Infrastructure role at genesis-molecular-ai full-time or part-time?
This is listed as a FullTime position. It is posted as a Software Engineer - Core Infrastructure role in the AI department at genesis-molecular-ai.
Which team or department does the Software Engineer - Core Infrastructure at genesis-molecular-ai belong to?
This Software Engineer - Core Infrastructure position is part of the AI department at genesis-molecular-ai. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Software Engineer - Core Infrastructure position at genesis-molecular-ai?
Click the "Apply Now" button on this page. You will be redirected to genesis-molecular-ai's official application portal hosted on ashby where you can submit your application directly.
When was the Software Engineer - Core Infrastructure job at genesis-molecular-ai posted?
This Software Engineer - Core Infrastructure position at genesis-molecular-ai was posted on Jan 27, 2026. Apply as soon as possible — early applications are often reviewed first.
Software Engineer - Core Infrastructure
genesis-molecular-ai
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