Senior Program Manager – Security and Performance

intersystems· System Development
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📍 Boston, MA

About this role

InterSystems is a global leader in healthcare data management and interoperability, providing mission-critical technology that powers hospitals, health systems, and national infrastructures worldwide. Our products underpin trusted healthcare and financial systems where performance, availability, and security are non-negotiable.

As a Senior Program Manager, you lead large-scale, complex, cross-functional initiatives across product, engineering, cloud, and AI. You operate across organizational boundaries, translating objectives aligned to corporate strategy into coordinated, measurable outcomes. You support and operationalize the security strategy across the portfolio, ensuring effective execution through structured programs.

Security and performance are horizontal capabilities across our stack. You partner with product, engineering, and architecture to maintain consistent execution across the portfolio.

Key Characteristics

  • Thrives in high ambiguity, competing priorities
  • Owns outcomes at a program level
  • Connects strategy to execution (systems thinker)
  • Influences without authority
  • Execution-focused; manages complexity
  • Communicates clearly across technical and business audiences

Key Responsibilities

  • Program Strategy, Execution & Delivery
    • Execute against existing program direction and strategic priorities, incorporating security and performance, and influencing future prioritization and execution
    • Translate program strategy into execution plans across multiple teams and projects
    • Lead concurrent projects to deliver program objectives
    • Coordinate execution with program managers across cloud, database, interoperability, HealthShare, and AI-enabled systems
    • Align scope, priorities, and dependencies to enable delivery
  • Cross-Functional Leadership & Stakeholder Management
    • Orchestrate work across product, engineering, architecture, compliance, and operations
    • Serve as integration point for dependencies, timelines, and deliverables
    • Manage senior stakeholders, including executive engagement
    • Communicate progress, risks, and decisions to support leadership action
    • Run structured updates and program reviews to maintain alignment
  • Program Performance, Health & Continuous Improvement
    • Monitor program performance and health against established KPIs, objectives, and milestones; contribute to KPI refinement
    • Manage risks, issues, and dependencies; escalate when needed
    • Maintain clear program visibility and enforce accountability
    • Improve execution, coordination, and operational effectiveness

Qualifications

  • Bachelor’s degree in Computer Science, Business, Engineering, or related field; advanced degree preferred
  • 10+ years leading large-scale, complex, cross-functional programs
  • Strong fundamentals in planning, scheduling, dependency and risk management
  • Experience managing performance to KPIs and driving accountability
  • Experience in cloud, healthcare, or enterprise technology environments preferred
  • Proven ability to influence senior stakeholders without direct authority
  • Strong communication and leadership skills
  • PMP or equivalent certification a plus




We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.

InterSystems is providing a current good faith estimate of the anticipated base salary range for this position depending on a variety of factors including experience, education, skills, and performance.

Other compensation may include a discretionary annual variable target incentive.

The company also provides generous employee benefits including:

  • Medical, vision, and dental insurance
  • Short-term and long-term disability, and life insurance
  • 401(k) Profit Sharing Contribution
  • Paid Time Off and Holidays
  • Parental Leave
  • Tuition reimbursement
The estimated base compensation range for this role is:
$147,000$185,000 USD

About InterSystems

InterSystems, a creative data technology provider, delivers a unified foundation for next-generation applications for healthcare, finance, manufacturing, and supply chain customers in more than 80 countries. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways. Established in 1978, InterSystems is committed to excellence through its 24×7 support for customers and partners around the world. Privately held and headquartered in Boston, Massachusetts, InterSystems has 38 offices in 28 countries worldwide. For more information, please visit InterSystems.com.

Frequently Asked Questions

Is the salary disclosed for the Senior Program Manager – Security and Performance position at intersystems?
The salary for this Senior Program Manager – Security and Performance role at intersystems is not publicly listed. Click "Apply Now" to learn more about the compensation package on their official careers page.
Where is the Senior Program Manager – Security and Performance position at intersystems located?
This Senior Program Manager – Security and Performance role at intersystems is based in Boston, MA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Which team or department does the Senior Program Manager – Security and Performance at intersystems belong to?
This Senior Program Manager – Security and Performance position is part of the System Development department at intersystems. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Senior Program Manager – Security and Performance position at intersystems?
Click the "Apply Now" button on this page. You will be redirected to intersystems's official application portal hosted on greenhouse where you can submit your application directly.
When was the Senior Program Manager – Security and Performance job at intersystems posted?
This Senior Program Manager – Security and Performance position at intersystems was posted on Jan 22, 2026. Apply as soon as possible — early applications are often reviewed first.
Senior Program Manager – Security and Performance
intersystems
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