Principal Technical Program Manager

lilasciences· Software
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📍 Cambridge, MA USA

About this role

Your Impact at LILA

Lila Sciences is an innovative early-stage company, and we're seeking a Principal Technical Program Manager to help lead our groundbreaking efforts in technology development. In this role, you will connect cutting-edge research with program execution, ensuring our initiatives not only meet current project needs but also pave the way for a transformative future.

What You'll Be Building

  • Guide the overall program, ensuring strategic alignment and translating research insights into actionable initiatives.
  • Evaluate and integrate emerging technologies to shape and refine program objectives in a dynamic environment.
  • Lead technical projects, ensuring the robustness and scalability of the technology stack while aligning with organizational goals.
  • Manage and maintain data integrity and relevance, collaborating across teams to set and monitor performance metrics.
  • Serve as the key interface between technical and business teams, effectively communicating complex outcomes and securing necessary resources.
  • Implement best practices for rapid experimentation and iteration, facilitating efficient and agile program progression.
  • Develop clear documentation and reporting to communicate vision, track progress, and align initiatives with organizational priorities.
  • Foster a culture of continuous innovation and experimentation by staying informed about technological advancements and recommending strategic improvements.

What You’ll Need to Succeed

  • Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field.
  • Proven experience in program management across various areas.
  • Strong analytical and problem-solving skills, with the ability to turn technical requirements into actionable program roadmaps.
  • Excellent organizational and communication skills, with experience leading cross-functional teams and driving programs to successful completion.

Bonus Points For

  • A proactive leader passionate about transforming research insights into tangible program value.
  • Skilled at managing both technical and operational aspects of early-stage program development, ensuring alignment with strategic business objectives.
  • Enthusiastic about emerging technologies and experienced in driving rapid experimentation and program iteration.

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range
$204,000$270,000 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Frequently Asked Questions

Is the salary disclosed for the Principal Technical Program Manager position at lilasciences?
The salary for this Principal Technical Program Manager role at lilasciences is not publicly listed. Click "Apply Now" to learn more about the compensation package on their official careers page.
Where is the Principal Technical Program Manager position at lilasciences located?
This Principal Technical Program Manager role at lilasciences is based in Cambridge, MA USA. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Which team or department does the Principal Technical Program Manager at lilasciences belong to?
This Principal Technical Program Manager position is part of the Software department at lilasciences. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Principal Technical Program Manager position at lilasciences?
Click the "Apply Now" button on this page. You will be redirected to lilasciences's official application portal hosted on greenhouse where you can submit your application directly.
When was the Principal Technical Program Manager job at lilasciences posted?
This Principal Technical Program Manager position at lilasciences was posted on Dec 22, 2025. Apply as soon as possible — early applications are often reviewed first.
Principal Technical Program Manager
lilasciences
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