Associate Director, Regulatory CMC
vaxcyte· Regulatory
About this role
Join our Mission to Protect Humankind!
Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.
Summary:
A hands-on role providing both strategic and operational activities. This role develops and executes multi-product global regulatory CMC strategies for investigational products and leads the preparation and filing of regulatory CMC submissions. Manages interactions with Health Authorities for CMC topics. Provides regulatory CMC guidance to various cross-functional teams and ensures all applicable global regulatory requirements are considered and incorporated into product development. Conducts routine regulatory surveillance and communicates new/changing regulations.
Essential Functions:
- Leads the preparation and review of CMC sections of global regulatory submissions, as well as the interactions and responses with regulatory agencies
- Member of technical development teams which require experienced interpretation of applicable EMA/FDA/ICH/Global regulations to ensure CMC compliance
- Defines CMC content (data and documentation) requirements for regulatory submissions and compiles/reviews this content for conformance with established requirements
- Provides CMC regulatory guidance to cross-functional teams and key stakeholders
- Manages regulatory assessment and guidance on product compliance topics including change controls, deviations, and GMP investigations throughout development
- Leads projects with cross-functional teams and acts as the primary regulatory CMC contact for assigned products and projects
- Represents company in Health Authority meetings and leads or supports CMC preparation activities for meetings with Health Authorities on CMC related matters
- Stays abreast of current and evolving regulatory CMC requirements, applies this knowledge to assigned projects, and shares knowledge and experience with others to support their development
- Participates in the design, development and implementation of department strategies, providing recommendations in area of expertise
Requirements:
Bachelor’s Degree in a scientific discipline (e.g. Biology, Chemistry, Pharmacy, Regulatory Affairs for Drugs, Biologics or Medical Devices). Minimum 10 years of experience working in vaccine or biotech industry, or in a related field, or the equivalent combination of education and experience. Other combinations of education and/or experience may be considered.
- Prior experience preparing/authoring CMC DS sections:
- BLA highly preferred.
- Post-approval supplements/variations highly preferred.
- INDs/IMPDs.
- Prior development or manufacturing experience is a plus.
- Computer software skills (LIMS, SAP, TrackWise, Veeva will be used).
- Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency.
- Excellent interpersonal skills to communicate difficult concepts.
- Strategic thinking and strong problem-solving skills
- Collaborates and communicates in an open, clear, complete, timely, and consistent manner
- Strong sense of planning and prioritization, and the ability to work with all levels of management
- Advanced knowledge in regulatory (FDA, EMA, Health Canada and ICH) guidelines
Reports to: Executive Director, CMC Regulatory
Location: San Carlos, CA / US Remote
Work Arrangement: Remote
Compensation:
The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range: $180,000 - $210,500 (SF Bay Area). Salary ranges for non-California locations may vary.
#LI-JN1
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
Frequently Asked Questions
Is the salary disclosed for the Associate Director, Regulatory CMC position at vaxcyte?
The salary for this Associate Director, Regulatory CMC role at vaxcyte is not publicly listed. Click "Apply Now" to learn more about the compensation package on their official careers page.
Where is the Associate Director, Regulatory CMC position at vaxcyte located?
This Associate Director, Regulatory CMC role at vaxcyte is based in San Carlos, California, United States. The position is listed as on-site or hybrid. Check the full job description or apply directly to confirm the work arrangement.
Which team or department does the Associate Director, Regulatory CMC at vaxcyte belong to?
This Associate Director, Regulatory CMC position is part of the Regulatory department at vaxcyte. See the full job description for more information about the team structure and responsibilities.
How do I apply for the Associate Director, Regulatory CMC position at vaxcyte?
Click the "Apply Now" button on this page. You will be redirected to vaxcyte's official application portal hosted on greenhouse where you can submit your application directly.
When was the Associate Director, Regulatory CMC job at vaxcyte posted?
This Associate Director, Regulatory CMC position at vaxcyte was posted on Apr 27, 2026. Apply as soon as possible — early applications are often reviewed first.
Associate Director, Regulatory CMC
vaxcyte
You'll be redirected to vaxcyte's official application page on Greenhouse.