Senior Research Associate (Contractor)
About this role
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking a Senior Research Associate (Contractor) as part of the Clincal Development team based in Philadelphia, PA.
Role Overview
This position will perform preclinical in vivo pharmacology and toxicology studies to support pipeline advancement. The ideal candidate will have experience in biology and oncology and in vivo studies with animal models. The successful candidate will work in a collaborative environment and is skillful in supporting multiple projects by conducting various in vitro and in vivo laboratory experiments.
Key Responsibilities
Work together with other team members to conduct in vivo studies with mouse, dog and NHP. Responsibility includes: Cell culture and banking, human PBMC isolation, Flow-cytometry based cell phenotyping analysis, animal dosing through injections of intravenous, intraperitoneal and subcutaneous. Tumor measurement through caliber and bioluminescent imaging, sample (tumor, blood and tissues) harvest, processing and analyzing.
Requirements
- BS or master’s degree in biological sciences.
- 3-5 years’ experience in a biological laboratory setting (industry preferred).
- Confidence in working with laboratory animals like mouse, rat, dog are essential. Extensive experience in animal handing, bleeding, necropsy, tissue collection and processing. Animal in vivo imaging (BLI) skills.
- Excellent animal dosing skills especially intravenous injection is required.
- Sense of ownership and integrity of their work. Demonstrated ability to work as part of a team. Good communication and interpersonal skills are required.
- Immunohistochemistry experience is a plus.
- Demonstrated organizational skills including but not limited to pay attention to details and multitasking.
- Cell culture, mouse handling and procedures (bleeding, injection, in vivo imaging, tissue dissection and analysis), not allergic to lab animals.
- Good verbal and written communication skills in English.
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Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.
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