Senior R&D Scientist - Inhalation Development

EVA Pharma is hiring Senior Scientist for the inhalation development team. The role will be responsible for hands-on formulation development, analytical characterisation, scale-up, and process validation of Generic Dry Powder Inhaler products — including capsule-based, blister-based, reservoir-based, dual capsule/blister inhalers, and generic nebulizers.

The role requires deep technical expertise in powder engineering and inhalation science, with the ability to independently drive development activities.

Key responsibilities:

DPI Formulation Development 

• Design and optimise DPI, MDI & Nebulizer formulations for capsule-based, blister-based, reservoir-based, and dual capsule/blister inhalers 

• Develop and evaluate device-formulation compatibility across all inhalation platform types 

• Apply particle engineering techniques — micronization, spray drying, powder blending — to achieve target aerodynamic profiles 

• Develop generic nebulizer formulations alongside DPI programmes 

• Execute feasibility, prototype, and optimisation studies with full scientific documentation 

Analytical Characterisation 

• Perform aerodynamic characterisation using NGI and DUSA for in-process and release testing 

• Apply laser diffraction and other particle sizing tools to characterise powder properties 

• Execute and interpret analytical data to guide formulation decisions and device selection 

• Support development and qualification of analytical methods specific to inhalation products 

Scale-Up & Process Validation 

• Lead scale-up activities from lab to pilot and commercial manufacturing scale 

• Define and optimise critical process parameters using QbD principles, DoE, and FMEA 

• Execute process validation protocols and compile validation reports 

• Identify and mitigate technical risks through the development lifecycle 

Tech Transfer to Manufacturing 

• Prepare technology transfer packages including formulation, process, and analytical documentation 

• Support on-site transfer activities at manufacturing scale and resolve technical deviations 

• Collaborate with production and engineering teams to ensure successful handover 

Bioequivalence Support 

• Contribute to bioequivalence protocol design for generic DPI products versus reference innovators 

• Prepare formulation and device rationale sections required for BE study initiation 

• Support interpretation of BE data from a formulation science perspective 

Scientific Guidance 

• Provide day-to-day technical guidance to 1–3 junior researchers working on DPI projects 

• Review experimental data, troubleshoot issues, and validate scientific conclusions 

• Maintain up-to-date knowledge of inhalation science, device technologies, and industry trends 

Education: 

PhD or Master's degree in Pharmaceutics, Pharmaceutical Sciences, or related field 

Overall Experience: 

8–10 years of hands-on experience in DPI development within the pharmaceutical industry  

Technical skills: 

• Proven formulation experience across capsule-based, blister-based, reservoir-based, and dual DPI formats 

• Hands-on expertise with NGI, DUSA, and laser diffraction for aerodynamic characterisation 

• Particle engineering skills: micronization, spray drying, and powder blending 

• Scale-up and process validation experience for inhalation products 

• Experience preparing technology transfer documentation for manufacturing handover 

• Contribution to BE protocol design or study initiation for generic DPI products 

• Familiarity with QbD, DoE, and FMEA-based risk management