Senior Scientist II Medicinal Chemistry, Oncology

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Key Responsibilities

• Conduct research in a large, multi-functional medicinal chemistry organization.
• As part of a project team, devise & execute synthetic routes to generate potential drug targets.
• Learn to use institutional software & tools to enable & accelerate design of new drug targets.
• Conceive & execute hypothesis-driven medicinal chemistry projects to optimize safety, ADME, & efficacy.
• Optimize routes to scale-up materials for key in vivo studies.
• Apply novel synthetic methodologies to access challenging targets.
• Analyze products using NMR, HPLC, LCMS, SFC, & other analytical tools to characterize reaction yields, product purity, & enantiomeric excess.
• Analyze & interpret in vitro & in vivo data from preclinical studies to inform design of next generation potential drug targets.
• Create scientific presentations & manuscripts for effective communication with internal stakeholders & international chemistry community.

Qualifications

Education & Experience

Must have a PhD in Organic Chemistry or other related scientific field & 2 years of academic or industry laboratory research experience.

Of experience required, must have 2 years with each of the following:

1. conceiving & executing synthetic organic chemistry projects with knowledge of contemporary synthetic techniques;
2. characterizing organic compounds using NMR, HPLC, LCMS, & SFC, to quantify reaction yields, product purity, & enantiomeric excess;
3. designing and executing multi-gram syntheses, multi-step synthesis campaigns, and reaction optimization;
4. using electronic lab notebooks;
5. acting as a lead scientist in an area of expertise on 1 or more projects; &
6. training & mentoring junior scientists.

Alternatively, would accept a MSc in Organic Chemistry or other related scientific field & 4 years of academic or industry laboratory research experience. Of experience required, must have 4 years with each of the following: (i), (ii), (iii), (iv), (v) & (vi).

Experience may be gained concurrently. Would accept any suitable combination of training, education & work experience.

Additional Information

Salary Range:  $148,500.00- $202,500.00 per year

Apply online at https://careers.abbvie.com/en or send resume to Job.opportunity.abbvie@abbvie.com. Refer to Req ID: REF49815W

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We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.  This job is eligible to participate in our short-term and long-term incentive programs.

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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