Scientist

Company Description

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.

Job Description

• We are seeking a highly motivated, results-oriented, self-starter who demonstrates personal accountability for outcomes and thrives on increasing levels of responsibility, to join a new and dynamic team responsible for successful development and characterization of clinical-scale manufacturing processes for Chimeric Antigen Receptor T cell (CART) therapies. 

• The successful candidate will contribute to the development and implementation of processes for lab-scale production and characterization of high-quality lentiviral vector (LVV) and its application for engineering CART cells.

Job Responsibilities: 

• Actively contribute to development and characterization, and successful execution of robust LVV production processes adherent and/ or suspension-based production, purification and formulation.

• Contribute to optimization of LVV transduction for CART manufacturing processes development as appropriate

• Contribute to innovation programs to enhance LVV and CART manufacturing technologies/ capabilities and work-processes as appropriate

• Contribute to Project Technical Teams and communicate and collaborate effectively to ensure effective interactions with all stakeholder groups

• Ensure high-quality, timely documentation in electronic laboratory notebooks and Technical Reports and contribute to Regulatory Filings and responses to Regulatory questions as appropriate.

• Present data/ strategy to scientists (and management) in internal venues (technical meetings, Project Team meetings) as appropriate.

Qualifications

Education & Experience:

BSc/ MSc with 5+ years or PhD degree in Virology/ Molecular Immunology/ Molecular Biology or related field or Chemical Engineering degree (with appropriate viral vector experience); experience with viral vector production/ purification processes and disposable manufacturing technologies a plus.

Technical Skills Requirements:

- Development and/ or execution of LVV/ other viral vector production and purification processes

- Molecular virology/ engineering and/ or production of recombinant viruses

- Culture of primary T cells, T cell molecular biology/ engineering

Additional Skills:BS/MS degree with 5+ years experience required, or PhD

Additional Information

Best Regards,

Anuj Mehta

973-967-3402